Biology · Principles and Processes in Biotechnology

According to the European Federation of Biotechnology (EFB), biotechnology encompasses both traditional view and modern molecular biotechnology. Which of the following components forms the core definition given by EFB?

1. Integration of natural science and organisms, cells, parts thereof, and molecular analogues for products and services
2. Exclusive use of genetically modified microorganisms for industrial enzyme production
3. Large-scale fermentation of wild-type microbes without cellular manipulation
4. Synthesis of artificial genomes inside cell-free in vitro systems only