Biology · Principles and Processes in Biotechnology

Why do bacteriophages serve as excellent cloning vectors compared to some plasmids in terms of copy number per bacterial cell?

1. Bacteriophages cannot replicate independently of host chromosomal DNA
2. Bacteriophages have a very high copy number of their genome within bacterial cells
3. Bacteriophages lack any recognition sequence for restriction endonucleases
4. Bacteriophages exclusively integrate into host chromosomes without extrachromosomal existence