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Biology · Principles and Processes in Biotechnology

हिन्दी

Given below are two statements: one is labelled as Assertion (A) and the other is labelled as Reason (R). Assertion (A): Ligases join foreign DNA to plasmid vectors by forming phosphodiester bonds between cut ends. Reason (R): DNA ligase acts on cut DNA molecules and joins their ends to reform a continuous sugar-phosphate backbone. In the light of the above statements, choose the correct answer from the options given below:

  1. Both (A) and (R) are true and (R) is the correct explanation of (A).
  2. Both (A) and (R) are true but (R) is NOT the correct explanation of (A).
  3. is true but (R) is false.
  4. is false but (R) is true.

Correct answer · Option 1

Both (A) and (R) are true and (R) is the correct explanation of (A).

Explanation

DNA ligases seal the nicks in the sugar-phosphate backbone by joining cut DNA molecules at sticky/blunt ends.
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