Biology · Principles and Processes in Biotechnology
हिन्दीGiven below are two statements: one is labelled as Assertion (A) and the other is labelled as Reason (R). Assertion (A): Ligases join foreign DNA to plasmid vectors by forming phosphodiester bonds between cut ends. Reason (R): DNA ligase acts on cut DNA molecules and joins their ends to reform a continuous sugar-phosphate backbone. In the light of the above statements, choose the correct answer from the options given below:
Correct answer · Option 1
Both (A) and (R) are true and (R) is the correct explanation of (A).
Explanation
DNA ligases seal the nicks in the sugar-phosphate backbone by joining cut DNA molecules at sticky/blunt ends.