Biology · Principles and Processes in Biotechnology

Given below are two statements: one is labelled as Assertion (A) and the other is labelled as Reason (R). Assertion (A): Ligases join foreign DNA to plasmid vectors by forming phosphodiester bonds between cut ends. Reason (R): DNA ligase acts on cut DNA molecules and joins their ends to reform a continuous sugar-phosphate backbone. In the light of the above statements, choose the correct answer from the options given below:

1. A
   Both (A) and (R) are true and (R) is the correct explanation of (A).
2. B
   Both (A) and (R) are true but (R) is NOT the correct explanation of (A).
3. C
   is true but (R) is false.
4. D
   is false but (R) is true.