Biology · PYQ NEET UG 2022

In gene therapy of Adenosine Deaminase (ADA) deficiency, the patient requires periodic infusion of genetically engineered lymphocytes because:

1. A
   Lymphocytes from patient’s blood are grown in culture, outside the body.
2. B
   Genetically engineered lymphocytes are not immortal cells.
3. C
   Retroviral vector is introduced into these lymphocytes.
4. D
   Gene isolated from marrow cells producing ADA is introduced into cells at embryonic stages.