Biology · BIOMOLECULES

Refer to the given potential energy profile diagram for an enzyme-catalysed reaction. Which of the following statements is correct regarding this reaction coordinate?

1. A
   The product (P) is at a higher energy level than substrate (S), making the reaction spontaneous and endothermic.
2. B
   The activation energy barrier is higher in the presence of an enzyme than in its absence.
3. C
   The transition state represents a completely stable intermediate requiring zero activation energy.
4. D
   The reaction is exothermic because the product (P) is at a lower energy level than substrate (S), and the enzyme reduces the activation energy barrier.