Biology · BIOMOLECULES

Why do lipids, despite having a molecular weight that does not exceed 800 Da, appear in the acid-insoluble fraction during tissue fractionation?

1. A
   They polymerize into giant covalent macromolecules of over 10,000 Da upon treatment with trichloroacetic acid.
2. B
   They form insoluble covalent bonds with acidic nuclear histones and sediment during filtration.
3. C
   They are part of disrupted cell membranes that form water-insoluble vesicles, which do not pass through the filter.
4. D
   They are degraded into volatile hydrocarbons that adhere tightly to cellulose filter membranes.